I was rehearsing with the band last weekend and as I played the rythm and some leads I started to pay attention to that distinct and easily recognizable "stratty" tone that is always there, the "quack" that the strat always does. no matter how you modulate/distort a real Fender Strat with single coils. It will quack, especially in positions 2 and 4.
It's something that actually bothers non strat lovers, but those of us who really dig the quack will enjoy it in any song/genre they're doing!